It can be used in agriculture as a seed treatment and biopesticide, helping plants to fight off fungal infections. A common method for the synthesis of chitosan is the deacetylation of chitin using sodium hydroxide in excess as a reagent and water.The biocontrol mode of action of chitosan elicits natural innate defense responses within plant to resist insects, pathogens, and soil-borne diseases when applied to foliage.The hemostatic agent works by an interaction between the cell membrane of erythrocytes (negative charge) and the protonated chitosan (positive charge) leading to involvement of platelets and rapid thrombus.Other higher quality trials indicated no significant effect of chitosan and no clinical justification for advising overweight patients to take chitosan.
